Zhongnuo Water Treatment designed and supplied a 5 m³/h GMP-compliant ultrapure water system for a biopharmaceutical company. The system combines double-pass reverse osmosis (RO), EDI technology, and UV sterilization to provide high-quality purified water for pharmaceutical manufacturing, laboratory applications, equipment cleaning, and CIP systems. Designed in accordance with GMP principles, the system ensures stable water quality, reliable operation, and fully automated control.

• Meeting stringent GMP purified water requirements.
• Maintaining stable water quality for continuous production.
• Removing ions, microorganisms, TOC and dissolved salts.
• Fully automatic monitoring and low operating costs.
• Reliable distribution to pharmaceutical production lines.

Municipal Water  ->  Raw Water Tank  ->  Raw Water Pump  ->  Multi-media Filter  ->  Activated Carbon Filter  ->  5 μm Cartridge Filter  ->  First-stage High-pressure Pump  ->  First-pass RO System  ->  First-pass Pure Water Tank  ->  Second-stage High-pressure Pump  ->  Second-pass RO System  ->  Second-pass Pure Water Tank  ->  EDI Booster Pump  ->  EDI System  ->  UV Sterilizer  ->  Ultrapure Water Tank  ->  Water Supply System  ->  Pharmaceutical Water Distribution System

The system integrates pretreatment, double-pass RO, EDI, UV sterilization, PLC automatic control, and sanitary piping to deliver consistent ultrapure water for GMP pharmaceutical production. The modular skid-mounted design simplifies installation, operation, and maintenance.

• Raw Water Tank

• Raw Water Pump

• Multi-media Filter

• Activated Carbon Filter

• 5 μm Cartridge Filter

• First-stage High-pressure Pump

• First-pass RO System

• Second-stage High-pressure Pump

• Second-pass RO System

• EDI Booster Pump

• EDI Module

• UV Sterilizer

• Ultrapure Water Tank

• PLC Control System

• Double-pass RO + EDI for high-purity water

• Conductivity as low as ≤0.2 μS/cm (depending on design)

• Continuous chemical-free EDI operation

• PLC automatic control with online monitoring
• Low TOC and microbial control
• GMP-compliant sanitary design
• Stable long-term operation and reduced maintenance

✓ Stable 5 m³/h ultrapure water production
✓ Reliable GMP-compliant water quality
✓ Continuous 24/7 operation
✓ Improved pharmaceutical production efficiency
✓ Reduced maintenance and operating costs
✓ Enhanced product quality and regulatory compliance

Q: Why use double-pass RO + EDI?
A: It provides higher purity and stable water quality required for pharmaceutical production.

Q: Is the system GMP compliant?
A: Yes, it is designed according to GMP water treatment principles.

Q: Can it be integrated with CIP/SIP?
A: Yes, it can be customized for pharmaceutical utilities.

Q: What water quality can be achieved?
A: Ultrapure water with very low conductivity and ion content.

Q: Is chemical regeneration required?
A: No. EDI operates continuously without chemical regeneration.

Q: Can the system run automatically?
A: Yes, PLC controls all operating processes.

Q: Can capacity be customized?
A: Yes, from 0.5 to over 100 m³/h.

Q: Does Zhongnuo provide installation?
A: Yes, commissioning, training and after-sales support are available.

• 23+ Years of Experience

• 20+ Professional Engineers

• GMP Water Treatment Expertise

• RO, EDI & Ultrapure Water Systems

• ISO-Certified Manufacturing

• Customized Engineering Solutions

• Complete EPC Service

• Global Projects in 100+ Countries

• 24/7 Technical Support